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Licensee MDPI, Basel, Switzerland. © 2023 by the authors. Schiavone, M. ; Vax, A. ; Formosa, C. ; Martin-Yken, H. ; Dague, E. ; François, J. M. A Combined Chemical and Enzymatic Method to Determine Quantitatively The Polysaccharide Components in The Cell Wall of Yeasts.

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Chao, T. ; Chang, G. ; Chen, W. Y. ; Chen, P. ; Mao, F. The Synergistic Effect of Rapamycin Combined with 5-Fluorouracil in BALB/c Mice Bearing CT-26 Tumor Cells. Kim, D. ; Min, K. ; Lee, S. Cell Cycle Dysregulation Is Associated with 5-Fluorouracil Resistance in Gastric Cancer Cells. Tada, R. ; Tanioka, A. ; Iwasawa, H. ; Hatashima, K. ; Shoji, Y. ; Ishibashi, K. ; Adachi, Y. ; Yamazaki, M. Structural Characterization and Biological Activities of a Unique Type β-D-Glucan Obtained from Aureobasidium pullulans. Shamas-Din, A. ; Kale, J. ; Leber, B. ; Andrews, D. Mechanisms of Action of Bcl-2 Family Proteins. Disclaimer/Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). Cancer 2014, 136, 493–502. Concept and principles of development. LMW-AP-FBG Reduces Growth of Syngeneic Transplanted CT-26 Tumors in Mice.

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Conflicts of Interest. Google Scholar] [CrossRef]. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (). Gupta, S. ; Prasad, S. ; Sethumadhavan, D. ; Nair, M. ; Mo, Y. ; Aggarwal, B. Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.

Concept And Principles Of Development

Jin, H. ; Li, M. ; Tian, F. ; Yu, F. ; Zhao, W. An Overview of Antitumour Activity of Polysaccharides. Data Availability Statement. Mata-Martínez, P. ; Bergón-Gutiérrez, M. ; Del Fresno, C. Dectin-1 Signaling Update: New Perspectives for Trained Immunity. Soleimani, A. ; Rahmani, F. ; Ferns, G. ; Ryzhikov, M. ; Avan, A. ; Hassanian, S. Role of The NF-κB Signaling Pathway in The Pathogenesis of Colorectal Cancer. Kim, Ji Hyeon, Jeonghyeon Seo, Huiwon No, Takao Kuge, Takahiro Mori, Hisashi Kimoto, and Jin-Kyung Kim. Kawata, K. ; Iwai, A. ; Muramatsu, D. ; Aoki, S. ; Uchiyama, H. ; Okabe, M. Concept development practice page 3.1.2. ; Hayakawa, S. ; Takaoka, A. ; Miyazaki, T. Stimulation of macrophages with the β-glucan produced by Aureobasidium pullulans promotes the secretion of tumor necrosis factor-related apoptosis inducing ligand (TRAIL). Biology 2021, 10, 854. Azwar, S. ; Seow, H. F. ; Abdullah, M. ; Faisal Jabar, M. ; Mohtarrudin, N. Recent Updates on Mechanisms of Resistance to 5-Fluorouracil and Reversal Strategies in Colon Cancer Treatment. Parzonko, A. ; Makarewicz-Wujec, M. ; Jaszewska, E. ; Harasym., J. ; Kozłowska-Wojciechowska, M. Pro-apoptotic properties of (1, 3)(1, 4)-β-D-glucan from Avena sativa on human melanoma HTB-140 cells in vitro. Gene 2020, 726, 144132. Western Blot Analysis. Anticancer Agents Med.

Nutrients 2021, 13, 242. Statistical Analysis. "Low-Molecular-Weight β-1, 3-1, 6-Glucan Derived from Aureobasidium pullulans Exhibits Anticancer Activity by Inducing Apoptosis in Colorectal Cancer Cells" Biomedicines 11, no. Informed Consent Statement. Tsujimoto, Y. ; Shimizu, S. Bcl-2 Family: Life-or-Death Switch. Wu, G. S. TRAIL as a Target in Anti-Cancer Therapy. Google Scholar] [CrossRef][Green Version]. Sun, M. ; Chen, X. ; Han, M. ; Yang, Y. N. ; Gao, X. ; Ma, X. ; Huang, Y. ; Li, X. ; Gai, M. T. ; Liu, F. ; et al. LMW-AP-FBG Reduces Viability of CT-26 Colon Cancer Cells. Materials and Methods. Goodridge, H. ; Wolf, A. ; Underhill, D. Beta-glucan recognition by the innate immune system. PLoS ONE 2015, 10, e0124809.

Remya, R. ; Rajasree, S. ; Suman, T. ; Aranganathan, L. ; Gayathri, S. ; Gobalakrishnan, M. ; Karthih, M. Laminarin based AgNPs using brown seaweed Turbinaria ornata and its induction of apoptosis in human retinoblastoma Y79 cancer cell lines. Cells and Cell Viability Assay. MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. Biomedicines 2023, 11, 529. Kim JH, Seo J, No H, Kuge T, Mori T, Kimoto H, Kim J-K. Biomedicines. Determination of Mitochondrial Membrane Potential. Multi-Caspase Assay. Greten, F. ; Grivennikov, S. I. Inflammation and Cancer: Triggers, Mechanisms, and Consequences. Bakshi, H. ; Quinn, G. ; Nasef, M. ; Mishra, V. ; Aljabali, A. ; El-Tanani, M. ; Serrano-Aroca, Á. ; Webba Da Silva, M. ; McCarron, P. ; Tambuwala, M. Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-κB/VEGF Pathways.

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Zhang, S. ; Liu, Y. ; Xiang, D. ; Yang, J. ; Liu, D. ; Ren, X. ; Zhang, C. Assessment of Dose-Response Relationship of 5-Fluorouracil to Murine Intestinal Injury. Author Contributions. Tsoni, S. ; Brown, G. D. Beta-Glucans and dectin-1. Nam, S. Tussilagone Reduces Tumorigenesis by Diminishing Inflammation in Experimental Colitis-Associated Colon Cancer. 2006, 26, 4131–4141. 2014, 34, 3329–3335. Kanda, Y. ; Ohata, H. ; Sakai, H. ; Mori, Y. ; Shiokawa, D. ; Yokoi, A. ; Owa, T. ; Ochiai, A. ; Okamoto, K. NF-κB Suppression Synergizes with E7386, an Inhibitor of CBP/β-Catenin Interaction, to Block Proliferation of Patient-Derived Colon Cancer Spheroids.

Fantini, M. C. ; Guadagni, I. Measurement of Apoptotic Cells. Nikolic, I. ; Kastratovic, T. ; Zelen, I. ; Zivanovic, A. ; Arsenijevic, S. ; Mitrovic., M. Cytosolic Pro-Apoptotic SPIKE Induces Mitochondrial Apoptosis in Cancer. Weng, W. ; Feng, J. ; Qin, H. ; Ma, Y. Molecular Therapy of Colorectal Cancer: Progress and Future Directions. Hayashi, N. ; Shoubayashi, Y. ; Fukudome, K. Hydrothermal processing of β-glucan from Aureobasidium pullulans produces a low molecular weight reagent that regulates inflammatory responses induced by TLR ligands. LMW-AP-FBG Reduces Mitochondrial Membrane Potential in CT-26 Cells. Yoshikawa, M. ; Ikeda, F. ; Kato, Y. ; Kuge., T. Induction of IFN-γ by a highly branched 1, 3-β-d-glucan from Aureobasidium pullulans in mouse-derived splenocytes via dectin-1-independent pathways.

Kimura, Y. ; Sumiyoshi, M. ; Suzuki, T. ; Sakanaka, M. Antitumor and Antimetastatic Activity of a Novel Water-Soluble Low Molecular Weight Beta-1, 3-D-Glucan (Branch Beta-1, 6) Isolated from Aureobasidium pullulans 1A1 Strain Black Yeast. B. Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing The Proinflammatory Microenvironment.