Sanotize’s “Revolutionary” Covid-19 Nasal Spray Bolstered By Phase Ii Trial
Among the 203 participants who used NONS, 13 tested positive (6. SaNOtize, alongside Ashford and St Peter's Hospitals NHS Foundation Trust and Berkshire and Surrey Pathology Services in the UK, have announced results of Phase II trials indicating that SaNOtize's nasal spray represents a safe and powerful antiviral treatment that could prevent the transmission of Covid-19, shorten its duration, and reduce the severity of symptoms in those already infected. The placebo nasal spray was normal saline and benzalkonium chloride which has virucidal activity. Follow us on social: LinkedIn, Twitter. Drug information provided by: IBM Micromedex. This medicine is usually given for up to 14 days or until your baby is ready to be weaned from nitric oxide treatment. For more information, visit View source version on Contacts. People with COVID infections using the spray also were more likely to have no symptoms at the end of the 16 days study. And I spend a lot of time with my grandchildren. The students that used Nitric Oxide Nasal Spray had a lower rate of infection with COVID, only 6% tested positive for COVID, compared to 26% in the control group. Please refer to user instructions). We look forward to expanding our clinical research and working toward regulatory approval in the United States and Canada. While NONS is not yet approved for sale in Canada or USA, SaNOtize is in discussions with regulatory authorities in both countries. The infected roommates had Delta and Omicron variants in almost a 50/50 split and there was no difference seen based on which variant it was.
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This medicine may cause a rare, but serious blood problem called methemoglobinemia. But the Covid-19 pandemic presented a new set of challenges, showing us both what's possible in terms of speed of response and what we need to do better to prepare for the next one. Glenmark said the Phase 3 trial in India met the key endpoints and demonstrated reduction of viral load of 94% in 24 hours and 99% in 48 hours, and was found to be safe and well tolerated in COVID-19 patients. 7% within 24 hours and by 99% within 48 hours of treatment with NONS. SaNOtize NONS was also shown to reduce SARS-CoV-2 viral load in a UK clinical trial (Phase II): "Patients with a self-administered nasal spray application found to have reduced SARS-CoV-2 log viral load by more than 95% in infected participants within 24 hours of treatment, and by more than 99% in 72 hours" [published on March 2021]. I did find an ongoing study in people with asymptomatic COVID-19, but the results are not yet available. Acid to make the nitric oxide. A 13% reduction in symptoms at day 16. In New Zealand, SaNOtize has registered its nasal spray with the New Zealand Medicines and Medical Devices Safety Authority, which permits the company to distribute and sell NONS over the counter immediately, the Vancouver-based company said. You can also use it when you start to get symptoms but the studies were not super impressive in NONS reducing COVID symptoms. "There is currently a lack of an antiviral therapy that is effective against COVID-19 and its variants, can prevent or shorten the course of the disease, reduce damage, lower the severity of COVID-19, and can be made widely and readily available to the public.
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Result shown in lab studies against viruses like SARS-CoV-2, H1N1, RSV. The evidence is mounting that NONS represents an effective, well tolerated antiviral treatment that significantly shortens the course of COVID-19. But when we are exposed to something as harmful as COVID, we want to destroy it before it can infect us. Similar results were observed in vaccinated and unvaccinated populations. Various research groups have also demonstrated the effectiveness of NO against a number of other respiratory viruses, including flu, rhinoviruses, and RSV. A nitric oxide-releasing solution as a potential treatment for fungi associated with tinea pedis. This medicine is inhaled into your baby's lungs through the mouth or nose. What are the Ingredients in NONS? Its antiviral nasal spray is now sold in 10 countries, registered as a Class I medical device in the EU, and has ongoing approval procedures elsewhere.
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Here is the cool thing about the NONS spray bottle: It has two chambers and two ingredients (sodium nitrite and citric acid) of the spray mix together when it is administered to form nitric oxide. London - Brent Research Ethics Committee. I won't pretend that it's very pleasant using the product, as there's a slight stinging sensation when using as directed (slightly inhaling when spraying each nostril). For years, the medical community has grappled with bacteria becoming drug-resistant and viruses evolving faster than we can generate vaccines. It took place during the delta and omicron surges, suggesting that the treatment may be effective against those variants. 6% in the control group (P<0. That's cool, but to be honest I'd really like to also see some evidence that there is a systemic lowering of the virus, like less virus in the blood. The were also able to show that it shortens the clinical progression, and the time a person has COVID Symptoms. In a randomised, double-blind, placebo-controlled Phase II trial that evaluated 79 confirmed cases of Covid-19, SaNOtize's early treatment significantly decreased the level of SARS-CoV-2, including in patients with high viral loads infected by the concerning UK variant of Covid-19. Additionally, the majority of patients included in the study were found to be infected with the UK variant of SARS-CoV-2, which has been a variant of concern in terms of treatments. The nasal spray was launched by the pharma company in partnership with SaNOtize.
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UK Clinical Trial Confirms SaNOtize's Breakthrough Treatment for COVID-19. Our Enovid Covid nasal spray review is based on our use of the product over the past month, both in the U. S. and while traveling in Europe. WHAT IS NITRIC OXIDE? Date of REC Opinion.
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Nitric oxide blocks entry into the nasal passage, kills the virus, and stops its replication, which is why viral load is reduced so rapidly with NONS. Israel, New Zealand OK sale of nasal spray that could prevent COVID-19 transmission. Nitric oxide is a naturally occurring molecule known to have antimicrobial properties, including a direct effect on SARS-CoV-2 and its variants, the virus that causes COVID-19. Under Technical Collaboration with: Sanotize Research and Development Corp. Canada. Only a few of people in a study (6. Another group has evaluated the antibacterial effects of NO released from biopolymers, finding that it kills a variety of bacteria and improves susceptibility in antibiotic-resistant bacteria. "The Phase 3 study results strongly support the safety and efficacy of NONS in the treatment of COVID-19 and its known variants, " said Gilly Regev, PhD, SaNOtize Co-Founder and CEO. " The multicentre, parallel-arm, double-blind trial analysed the safety and efficacy of NONS against saline nasal spray enrolling 306 non-hospitalised patients across 20 clinical sites in the country. Storage: Store at room temperature. FabiSpray has been designed to destroy the SARS-CoV-2 virus that causes Covid-19 in the upper airways. The SaNOtize treatment kills the virus in the upper airways, preventing it from incubating and making its way to the lungs.
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1 years, 0 months, 1 days. The median time to virological cure was four and eight days in the NONS arm and the placebo arm, respectively. Two studies have shown improvement in people with COVID-19 using the nasal spray, but there are no published data I can find to show that the spray prevents infection in the first place. The company was listed on the Dow Jones Sustainability Index (DJSI), one of the world's most respected and widely accepted sustainability benchmarks, under the category of emerging markets (2021) for the fourth consecutive year. For best results, it is suggested to avoid other immediate use of nasal sprays or similar treatments, for at least 30 minutes after using VirX.
Let me tell you, I really wished I had it.